Now living in a cozy Tuscan Villa with his wife and their two children, Ezio spends his time enjoying the company of family, old friends, and cultivating his vineyards. The life of this former Assassin Mentor will not stay quiet for long. One day, a mysterious Assassin shows up at Ezio's door quite unexpectedly, begging for Ezio's aid. Will this old Assassin's fire die out before he can save the ones he loves, or will it burn brightly one last time?