Six challenging months after the horrific events of 28 Days Later... (2002), when the unstoppable Rage Virus decimated the entire city of London, the U.S. Army has restored order and is repopulating the quarantined city. However, after the first wave of returning refugees, an unsuspecting carrier of the highly transmittable pathogen enters the dead city, and unknowingly re-ignites the spread of the deadly infection. Indeed, the virus is not yet dead, and this time, it is more dangerous than ever. Will the nightmare begin again?